A Multicenter, Non-interventional Study to Assess the Barriers to Initiation of Antiretroviral Treatment in Treatment-naïve HIV-1 Infected Subjects

Study Objective

Primary objectives:

• To assess the degree of discordance of perceived barriers to treatment initiation between physicians and treatment-naïve HIV-1 infected patients

Secondary objectives

• To investigate possible physician-described reasons for deferring HIV treatment initiation in antiretroviral-naive HIV-1 infected subjects
• To investigate possible patient-described reasons for deferring HIV treatment initiation in antiretroviral-naive HIV-1 infected subjects

Participation conditions

Inclusion criteria

1. Age ≥ 18 years
2. Chronic HIV-1 infection
3. Under care for HIV-1 infection at the clinical site for the last 180 days or more
4. Antiretroviral treatment naive
5. Initiation of HIV-1 therapy not explicitly agreed upon and not scheduled within the next 90 days from date of consent (regardless whether treatment is indicated per applicable guidelines or not)
6. A CD4 count available within the last 180 days (irrespective of CD4 count value)
7. Able to read and write in one of the study languages
8. Willing and able to provide informed consent, as evidenced by signing a subject Informed Consent Form.

Exclusion criteria

1. Acute HIV infection (< 180 days from presumed date of infection)
2. Participation in the “START” clinical study, or within a similar clinical trial that may randomise the subject to start or defer ART.
    

Centre Hospitalier de Luxembourg