Health follow-up examination of the participants of the ORISCAV-LUX study conducted in 2008 (more information here: http://www.oriscav.lih.lu/ )

8 years later, this study will among others:

- Describe the evolution of cardiovascular risk factors and related diseases between 2008 and 2016;
- Study the link between arterial stiffness and cognitive function in elderly people;
- Analyze the impact of low vitamin D status on cognitive performance;
- Investigate the link between stress biomarkers and metabolic syndrome in the general population;
- Assess physical frailty by measuring objectively physical condition and cognitive function;
- Analyze the link between weight, body composition and physical frailty.
The visit lasts around 4 hours but can be proposed to be done in 2 parts, depending of the choice of the participant.

Study Objective 

The study will take place in 4 steps:

1. Firstly, the participants to ORISCAV-LUX1 will be contacted and proposed to take part in ORISCAV-LUX2; if they agree:

2. Secondly, they will be asked to fill a questionnaire on their health (online or paper version).

3. Thirdly, they will be contacted to arrange an appointment with a nurse in Strassen, Esch-sur-Alzette or Ettelbruck. This visit will last about 4 hours and they will undergo different examinations concerning:

- Blood pressure and pulse;
- Cardiac rhythm (ECG);
- Arterial stiffness;
- Height and weight, waist, hip and thigh circumferences;
- Fat mass, fat free mass and muscle mass;
- Cognitive ability;
- Physical activity measurement;
- Collection of a small hair sample for future analysis on pollution exposure.

4. Finally, they will be invited to a collection center of Ketterthill laboratory for a blood test and urine collection.

Participation conditions

Inclusion criteria

This survey is addressed to each adult, man and woman, who took part in ORISCAV-LUX1.

Further information:

- They (and their doctor if they wish so) will receive: the results of blood and urine tests, their ECG with medical feedback, an assessment of their lab results, their blood pressure values, their height and weight with the BMI.
- Part of the samples as well as all data collected will be used later on for scientific research in chronic disease epidemiology, including cardio-metabolic and neurodegenerative diseases, in particular to study genetic predispositions and for future international studies.
- In any case, their anonymity will be preserved.
- Their participation is voluntary, they can refuse at any time without any consequences.
- http://www.oriscav.lih.lu/OriscavLux/ORISCAVLUX2.aspx

List of participating centres: Luxembourg Institute of Health (LIH)